reuters:

Syria’s defense minister and President Bashar al-Assad’s brother-in-law were killed in a Damascus suicide bomb attack carried out by a bodyguard on Wednesday, the most serious blow to Assad’s high command in the country’s 16-month-old rebellion.

The bomber, said by a security source to be a bodyguard assigned to Assad’s inner circle, struck a meeting attended by ministers and senior security officials as battles raged within sight of the presidential palace.

State television said Defence Minister Daoud Rajha and Assad’s brother-in-law Assef Shawkat, the deputy defence minister, had been killed in a “terrorist bombing” and pledged to wipe out “criminal gangs”.

A Syrian security source confirmed Shawkat, 62, - a pillar of Assad’s rule - was killed and said intelligence chief Hisham Bekhtyar was wounded. State television said Interior Minister Mohammad Ibrahim al-Shaar had also been wounded in the blast.

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